Cargo Delivery – Deliver Journal http://deliverjournal.com/ Tue, 24 May 2022 15:09:38 +0000 en-US hourly 1 https://wordpress.org/?v=5.9.3 http://deliverjournal.com/wp-content/uploads/2021/05/deliver-journal-icon-150x150.png Cargo Delivery – Deliver Journal http://deliverjournal.com/ 32 32 The next delivery of infant formula to Pennsylvania, Biden announced http://deliverjournal.com/the-next-delivery-of-infant-formula-to-pennsylvania-biden-announced/ Tue, 24 May 2022 13:50:40 +0000 http://deliverjournal.com/the-next-delivery-of-infant-formula-to-pennsylvania-biden-announced/

WASHINGTON, DC (WTAJ) — Another infant formula shipment is expected to leave Europe and is destined to reach Pennsylvania in the coming days, according to President Biden.

After 78,000 pounds of formula landed in Indianapolis, the president caught on Twitter to announce that the next delivery was in preparation.

“I have an update on Operation Fly Formula. We have secured a second flight to transport Nestlé specialty infant formula to Pennsylvania. keep you posted.

President Joe Biden on Twitter

According to a White House statement, 114 pallets of formula would leave Ramstein Air Force Base in Germany and land at Washington Dulles International Airport, then head north via FedEx to a Nestlé factory in Pennsylvania. The Gerber Good Start Extensive HA Expedition can fill approximately 1.4 million 8 oz. bottles, they said.

The second shipment, which is expected to arrive in the “next few days,” was announced by Biden just days after the United States received 78,000 pounds of formula through its Operation Fly Formula. The operation is the result of a major nationwide shortage caused by the closure of Abbott Nutrition by the FDA.

The manufacturer can now receive priority orders for raw materials such as sugar and corn syrup for infant formula, which the White House says will allow the manufacturer to quickly increase production by a third.

Nestlé said that over the past few months it has been working “around the clock” to address formula shortages and help meet demand.

“We have significantly increased the amount of our formulas available to consumers by increasing production and accelerating the general availability of products at retailers and online, as well as in hospitals and home health care for the most vulnerable. vulnerable,” the company said in a statement.

US regulators and Abbott Nutrition hope to reopen its Michigan plant next week, but it will take about two months before the product is ready for delivery. The Food and Drug Administration eased infant formula import requirements this week to try to ease the supply shortage, which has left store shelves empty of some brands and some retailers rationing supplies for parents nervous about feeding their children.

Michael Conroy and The Associated Press contributed to this story.

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First shipment of infant formula arrives in US from Europe http://deliverjournal.com/first-shipment-of-infant-formula-arrives-in-us-from-europe/ Sun, 22 May 2022 23:00:41 +0000 http://deliverjournal.com/first-shipment-of-infant-formula-arrives-in-us-from-europe/

A military cargo plane carrying the first shipment of infant formula from Europe to help tackle a critical shortage in the United States landed in Indianapolis on Sunday, and the White House said a second flight had been made. organized. A recall on February 17 by the largest baby formula maker Abbott Laboratories and the closure of its manufacturing plant in Sturgis, Michigan, during an investigation by the United States Food and Drug Administration, created the one of the largest infant formula shortages in recent history for American families.

“This is an important step, but it is by no means the only step that needs to take place. We will continue to work as the President has instructed us to seek out all opportunities to increase supply,” said the Agriculture Secretary Tom Vilsack, who greeted the aircraft on arrival. “This particular formula is for a very, very small percentage of children. About 17,000 children in the country are basically the beneficiaries of this particular formula,” he said.

President Joe Biden’s administration is looking to stock empty shelves with 1.5 million containers of Nestlé specialty infant formula. Biden last week invoked the Cold War-era Defense Production Act to help boost supplies. The White House said on Sunday that a second flight carrying a formula would depart from Ramstein Air Base in Germany in the coming days. The White House said Abbott and a second infant formula maker, Reckitt, were the first companies to receive priority status for raw material supplies under the Defense Production Act.

Nestlé also said more shipments would arrive in the coming days. Troops used forklifts to unload crates of cargo from the plane in Indianapolis and onto trucks heading to distribution centers. The White House said 78,000 pounds (35,000 kg) of specialty infant formula – enough for 500,000 bottles – arrived on the flight.

Abbott, the largest U.S. supplier of powdered infant formula, has closed its Michigan plant following reports of bacterial infections in four infants, worsening a shortage among several manufacturers that began with supply chain issues. related to the coronavirus pandemic. Abbott chief executive Robert Ford on Sunday apologized for the shortage and promised to fix it, adding that the plant would reopen the first week of June and it would take six to eight weeks for products to reach store shelves.

“We are sorry for all the families we have abandoned since our voluntary recall exacerbated the formula shortage in our country,” he wrote in a Washington Post column. New York City Mayor Eric Adams declared a state of emergency on Sunday to prevent baby formula prices from rising.

“This emergency executive order will help us crack down on any retailer seeking to take advantage of this crisis by raising prices for this essential good,” Adams said in a statement.

(This story has not been edited by the Devdiscourse team and is auto-generated from a syndicated feed.)

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EIB and Lithuania sign advisory services agreement to support green inland freight navigation http://deliverjournal.com/eib-and-lithuania-sign-advisory-services-agreement-to-support-green-inland-freight-navigation/ Fri, 20 May 2022 12:31:14 +0000 http://deliverjournal.com/eib-and-lithuania-sign-advisory-services-agreement-to-support-green-inland-freight-navigation/

The European Investment Bank (EIB) and the Lithuanian Inland Waterways Authority have signed a consultancy services agreement to support the construction of zero-emission electric transport vessels to initiate freight transport between the two major cities of Klaipėda and Kaunas. At the end of 2021, an ambitious project to introduce an electric tug was launched in Lithuania. With no CO2 emissions, this project will play a crucial role in revitalizing freight transport on Lithuania’s largest river, the Nemunas (aka Neman), and developing greener transport chains in the country.

EIB experts as well as external service providers mobilized by the European investment advisory platform will provide advice to LIWA to analyze the feasibility of the project, as well as its financing options. The EIB, through the EIAH, will also provide market information on providers and operators, as well as any potential regulatory and competition issues.

“I am delighted that EIB advisory services are supporting this innovative transport infrastructure project, which will help achieve Lithuania’s climate ambitions by significantly reducing air pollution and traffic,” said Thomas Östros, Vice -President of the EIB in charge of the activities of the EIB in the Baltic countries. “The EIB is fully committed to advising and financing investment projects that promote innovative and green solutions for transport in the European Union.”

LIWA CEO Vladimiras Vinokurovas said, “The Lithuanian Inland Waterways Authority is the administrator of waterways of national importance. the national carbon footprint of transport by replacing fossil fuel trucks with electric barges All Lithuanian companies, especially state-owned ones, should strive for a green path and a sustainable economy not only in the final result, but also in all the intermediate chains. As supply chains become more sustainable, advanced solutions are integrated into a single chain and deliver maximum benefits. Water transport is the most environmentally friendly, accident-free, unlimited and cost-effective of all modes.

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Air France-KLM signs cargo agreement with French shipping company CMA CGM http://deliverjournal.com/air-france-klm-signs-cargo-agreement-with-french-shipping-company-cma-cgm/ Wed, 18 May 2022 10:08:00 +0000 http://deliverjournal.com/air-france-klm-signs-cargo-agreement-with-french-shipping-company-cma-cgm/

PARIS, May 18 (Reuters) – French shipping company CMA CGM is to take a stake in Air France-KLM (AIRF.PA) in an air cargo partnership, betting on growing demand for flying goods around the world as supply chains remain blocked in the wake of the pandemic.

CMA CGM will take up to 9% of Air France-KLM, worth around 240 million euros ($252 million) based on Tuesday’s closing price, as part of a possible capital increase by the airline group for the duration of their partnership which is initially set to operate for 10 years, the two companies said.

This will make CMA CGM the fourth-largest shareholder, according to Refinitiv data, and mirrors a similar move planned by shipping company MSC, which has teamed up with German Lufthansa (LHAG.DE) for a potential bid for the airline. Italian ITA Airways. Read more

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Air France-KLM shares rose 3.5% at the start of the session, making it one of the best performers in the Paris SBF-120 stock index (.SBF120).

Marseille-based CMA CGM, one of the world’s largest container shipping companies, created an air cargo division last year as part of an effort to develop non-sea logistics.

Rising shipping profits, linked to high freight rates since the COVID-19 pandemic, have enabled CMA CGM and other shippers to invest in other forms of transport to build the resilience of shipping chains. global supplies and protect against a downturn.

“All the shipping container carriers are making money in recent years and are looking to put them all smartly to expand their service offerings, to include more modes, like air, and to move into full transportation,” said Peter Sand, chief analyst at air and ocean freight rate benchmarking platform Xeneta.

He added that customers would benefit from shorter transit times for goods.

CMA CGM, a private company controlled by the Saadé family, last month bought the car transport company Gefco, co-owned by Russian Railways (RZD) and car manufacturer Stellantis (STLA.MI). Read more

Air France-KLM and CMA CGM said their partnership should generate “significant revenue synergies” and said they had a “strong ambition to invest and grow sustainably” in the air cargo market. They will also pool their global business resources.

As a shareholder, the Dutch state “supports the partnership which is good for the financial situation”, said a spokesman for the Ministry of Finance.

ING analysts hailed the deal, which will help the French carrier capitalize on some of the business that was not very profitable before the pandemic. Combining forces with CMA gives it “material” market share, they said in a note.

The partnership with Air France-KLM covers a combined fleet of 10 all-cargo aircraft, including four at CMA CGM Air Cargo and six at Air France-KLM. Together they also have 12 aircraft on order.

It also covers Air France-KLM’s belly aircraft capacity, covering cargo carried on the airline group’s more than 160 long-haul passenger aircraft.

Air France-KLM competes in the cargo market with European carriers including Lufthansa and cargo specialist Cargolux, as well as major carriers in the Gulf and Asia.

The separate networks of Air France, KLM and Martinair – a subsidiary of the group – rank the group around eighth in the world ranking of cargo airlines by traffic, according to statistics from the International Air Transport Association.

Air France-KLM’s major shareholders, including the French and Dutch governments, have backed securing a seat on CMA CGM’s board of directors at the company’s next board meeting on May 24. , the partners said.

The combination is subject to anti-trust approval. The final size of CMA’s stake will be determined by the airline’s planned capital increase of up to €4 billion. Read more

Some 2 billion tonnes of global cargo are moved annually in containers by sea, while air cargo volumes are around 60-70 million tonnes, Xeneta’s Sand said.

“Cargo moves from ocean to air from time to time when conditions are right.”

In a recent example of how COVID lockdowns are prompting businesses to use the air for faster deliveries, General Electric’s (GE.N) healthcare unit flew dye used for testing and medical testing to help tackle US shortages caused by the suspension of its Shanghai factory. Read more

Nestlé (NESN.S) is also flying baby formula from Europe to restock US supermarket shelves due to a shortage there. Read more

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Reporting by Tim Hepher and Gus Trompiz; Additional reporting by Anthony Deutsch in Amsterdam and Jonathan Saul in London; Editing by Josephine Mason, Jason Neely and Kim Coghill

Our standards: The Thomson Reuters Trust Principles.

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First air cargo of durian lands at Nanning airport http://deliverjournal.com/first-air-cargo-of-durian-lands-at-nanning-airport/ Sun, 15 May 2022 21:30:00 +0000 http://deliverjournal.com/first-air-cargo-of-durian-lands-at-nanning-airport/

The first batch of durians exported by air from Thailand have arrived at Nanning Wuxu International Airport in Guangxi, China, following an effort to boost air trade between the two countries.

The fruit arrived at the airport on a Tianjin Air Cargo flight, which landed about two hours after taking off from Bangkok.

“This is good news for durian producers,” said Alongkorn Ponlaboot, adviser to the Minister of Agriculture and Cooperatives.

The durian shipment was made possible after Tianjin Air Cargo, a carrier based in China’s Beijing-Tianjin-Hebei region, launched a cargo service linking Nanning, capital of Guangxi Zhuang Autonomous Region (southern China). China), and Bangkok.

The service is expected to boost exports by air between China and Thailand, especially durian exports, Alongkorn said.

The route followed the decision of the General Administration of Customs of the People’s Republic of China (GACC) on April 1 to allow fruit imports from overseas.

The GACC then approved Nanning Wuxu International Airport in the province as a gateway for fruit imported from Thailand.

Alongkorn said Agriculture and Cooperatives Minister Chalermchai Sri-on had also instructed state agencies to boost exports by sea to ease congestion at land checkpoints during the season. durian harvest.

About 40 percent of the durian will be exported overland, while about 5 percent will go through the China-Laos high-speed railway and by air.

This batch of durian was intentionally harvested for export by air, reducing the risk of fruit damage during transfer. This is less likely to happen during land and sea transport.

The speed with which durian can reach the Chinese market will also help ensure the freshness of durian, which is in high demand among Chinese consumers.

Currently, the airport also has live and frozen aquatic food quality control facilities, which could further boost trade between Southeast Asia and China.

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Polskie Grnictwo Naftowe i Gazownictwo SA: First shipment of liquefied natural gas delivered by tanker chartered by PGNiG http://deliverjournal.com/polskie-grnictwo-naftowe-i-gazownictwo-sa-first-shipment-of-liquefied-natural-gas-delivered-by-tanker-chartered-by-pgnig/ Sat, 14 May 2022 10:10:02 +0000 http://deliverjournal.com/polskie-grnictwo-naftowe-i-gazownictwo-sa-first-shipment-of-liquefied-natural-gas-delivered-by-tanker-chartered-by-pgnig/

The tanker “Maran Gas Apollonia” with a cargo of more than 65,000 tons of liquefied natural gas has arrived at the LNG terminal president Lech Kaczyński in Świnoujście. This is the first delivery made on a vessel chartered by the PGNiG group. This is also the first shipment that PGNiG has received from Venture Global LNG, which will soon be a major supplier to Poland.

This is the first time that the LNG cargo has been delivered by a vessel chartered by the PGNiG Group, opening a new chapter in the Group’s operations in the global LNG market. So far, we have only purchased LNG shipments with assured transport. Now we can also buy gas directly from liquefaction terminals under free on board contracts. This definitely expands our possibilities for securing liquefied natural gas volumes,”underlined Iwona Waksmundzka-Olejniczak, President of the Management Board of PGNiG SA.The last year in the European gas market has clearly demonstrated the importance of access to diversified and reliable gas sources. LNG provides such access, hence the enormous growing interest in liquefied natural gas among European companies. By acting in advance, PGNiG has firmly established itself in the LNG market, so we can now effectively use our skills and capabilities to enhance the energy security of our customers.“, she added.

The tanker “Maran Gas Apolonia” brought more than 65,000 tons of LNG, which corresponds to more than 90 million cubic meters of natural gas after regasification. The cargo was loaded at Calcasieu Pass Liquefaction Terminal in Louisiana, owned by Venture Global. From next year, PGNiG will start receiving 1.5 million tonnes of LNG per year (2 bcm of natural gas, after regasification) from the Calcasieu Pass terminal under a long-term contract. PGNiG also has a long-term agreement with Venture Global to receive 4 million tonnes per year (approximately 5.3 bcm of natural gas, after regasification) from the Plaquemines liquefaction terminal in Louisiana.

“Venture Global is proud to celebrate this historic milestone with our most important partner and customer, PGNiG,” said Mike Sabel, CEO of Venture Global LNG. “Poland’s foresight and proactive strategic planning for its energy security needs put it in a strong position today. Our company is proud that, under long-term agreements with PGNiG, we will soon be supplying LNG, which will help meet a significant part of Poland’s gas demand. These long-term FOB contracts will make PGNiG not only a consumer but also a regional leader in LNG supply and trading,” Mr. Sabel added.

The two long-term contracts with Venture Global are based on the FOB formula. In order to receive the gas purchased under these contracts, PGNiG has started to develop its own fleet of LNG carriers. The Group has chartered eight units, each with a capacity of 174,000 tons of liquefied natural gas, which will be built exclusively for the PGNiG Group. The first two tankers will enter service next year, the next two – in 2024, and the remaining four – in 2025.

Due to the recent intensification of LNG imports by PGNiG, the Group has decided to charter three vessels as of this year, including two in the first half of 2022. One of them is “Maran Gas Apollonia”, whose owner is Maran Gas Maritime, a company owned by the Angelicoussis Group. Maran Gas Maritime will also own two of the eight LNG carriers under construction for the PGNiG Group.

“Maran Gas is truly honored to be PGNiG’s maritime partner in this major milestone. This ‘first’ comes shortly after PGNiG and Maran Gas entered into long-term charter contracts for 2 LNG carriers to support the Poland’s efforts to diversify and strengthen its LNG supply chain Faced with the acceleration in the growth of trade, in a world much more fragmented than a few months ago and with growing environmental challenges, such a partnership between two strong European companies is more topical than ever”, Sveinung JS Stohle, Deputy Managing Director of the Angelicoussis Group. “Maran Gas’ mission is to provide world-class shipping services to its customers in a safe, reliable and sustainable manner while embracing the energy transition. We do this with integrity, focusing on the efficient and timely delivery of shipments in line with our customers’ expectations. Last but not least, at Maran Gas, we take a long-term view of our relationships, our people and our vessels. We are therefore very pleased to be a key transportation supplier for PGNiG’s long-term LNG supplies to the Polish market,” he added.

The LNG delivered by “Maran Gas Apollonia” is already the 17th LNG delivery received by PGNiG in Świnoujście in 2022 and the 165th since the start of the terminal’s operation. After the recent development, starting this year, the Świnoujście terminal has a regasification capacity of 6.2 Gm3 of gas per year, compared to 5 Gm3 previously. Thanks to new investments, the terminal’s regasification capacity will increase to 8.3 bcm of gas per year in 2024. PGNiG has reserved 100% of the facility’s regasification capacity.

On May 6, PGNiG Group took delivery of the first LNG shipment outside Poland, which was delivered to the LNG terminal in Klaipeda, Lithuania. Most of the gas delivered there was routed to Poland via the recently opened Poland-Lithuania gas pipeline, and some was offered to the market in the Baltic states.

About PGNiG Group

The PGNiG group is the leader of the Polish gas market. It operates in the exploration and production of natural gas and crude oil, international gas trading, the sale and distribution of gas and liquid fuels, as well as the production of heat and electricity. The PGNiG group consists of more than 30 companies with a total of 25,000 employees. It operates, among others, in Poland, Lithuania, Norway, Pakistan and the United Arab Emirates. The parent company of the Group, PGNiG SA, is one of the largest companies listed on the Warsaw Stock Exchange.

About Venture Global LNG
Venture Global is a long-term, low-cost supplier of US LNG from resource-rich North American natural gas basins. Venture Global’s first facility, Calcasieu Pass, began producing LNG in January 2022. The company is also building or expanding an additional 60 MTPA of production capacity in Louisiana to provide clean, affordable energy to the world. The company is developing carbon capture and sequestration (CCS) projects at each of its LNG facilities.

About the Angelicoussis Group
Founded in 1947, the Angelicoussis Group has grown to become one of the largest private shipowners in the world. The Group owns 163 vessels in the LNG, tanker and dry bulk sectors, 13 of which are under construction. As a private company focused on shipping, we keep a large portion of our profits within the company. The strength of its balance sheet allows the group to weather economic cycles and provides flexibility to deploy capital when opportunities arise. Maran Gas Maritime was founded in 2003 as the gas vessel management business unit of the Angelicoussis Group, performing all technical, operational and commercial management functions in-house. Over the past 19 years, Maran Gas Maritime has accumulated a wealth of experience which has enabled the company to offer cutting-edge services and grow through long-term partnerships with leading industry players. .

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Flytrex and Jersey Mike’s Ink new drone delivery partnership http://deliverjournal.com/flytrex-and-jersey-mikes-ink-new-drone-delivery-partnership/ Thu, 12 May 2022 15:29:38 +0000 http://deliverjournal.com/flytrex-and-jersey-mikes-ink-new-drone-delivery-partnership/

Jersey Mike’s takes its motto literally. The sandwich chain, which markets itself as ‘A Sub Above,’ announced Thursday a partnership with Israeli drone delivery provider Flytrex to deliver subs across the sky to customers in Holly Springs, Carolina North. Customers will be able to have Jersey Mike orders sent directly to their backyard in five minutes.

The new partnership strengthens Flytrex’s presence in North Carolina, where it delivers everything from groceries to chicken wings to approximately 10,000 residents in the tri-city center of Holly Springs, Fayetteville and Raeford.

Flytrex flies in the state in conjunction with local partner, Causey Aviation Unmanned. The companies recent agreement with the FAA allows drone deliveries within a 1 nautical mile radius.


Watch: Drones in the backyard FAA grants home delivery to Flytrex


“In partnership with Flytrex, we’re thrilled that our fans can enjoy the freshest sub sandwiches transported straight to their backyards – it’s truly a sub from above,” said Scott Scherer, CIO of Jersey Mike’s Franchise Systems Inc.

Jersey Mike customers can order drone delivery through the Flytrex app. The app provides updates to customers along the route, similar to third-party food delivery services like Uber Eats or DoorDash. Once the drone arrived, the order was lowered to the customer’s garden by wire.

Flytrex CEO Yariv Bash hinted that the partnership is still in its infancy. “We’re thrilled to team up with Jersey Mike’s to deliver subs to the skies of North Carolina and look forward to expanding our partnership wherever they deliver their delicious food,” he said in a statement. Press release.

“Drone delivery is accelerating faster than anyone could have imagined,” Bash continued, “and we’re excited to be at the forefront of this movement – using our technology to ensure retailers and restaurants can stay ahead of the super-fast delivery curve.”

Bash and Flytrex have been busy for the past few months. Most notably, the drone delivery provider last month launched a service in Granbury, Texas, in conjunction with Brinker International, which owns brands like Chili’s Grill & Bar and Maggiano’s Little Italy. This comes after Flytrex secured a $40 million fundraise in November to expand operations.


Read: Wings over Texas: Flytrex drones deliver It’s Just Wings in Lone Star State

Read: Flytrex will fly chicken wings in North Carolina


According to Flytrex, the company has made more drone deliveries than any other company operating in the United States.

But Bash aims even higher. Flytrex is nearing the end of a years-long regulatory process to obtain airworthiness certification from the FAA. That would give the company’s drone delivery network far more leeway than a commercial drone certification, which is limited by FAA regulations for unmanned aircraft systems (UAS).

“The difference is huge. You can buy a commercial drone at Best Buy, whereas it takes three to five years to certify an aircraft. So to the untrained eye, they all look the same: a box with a few propellers,” Bash told Modern Shipper in an October interview. “But from an aviation perspective, these are very different machines from most of the ones you see flying overhead.”

You might also like:

FAA greenlights Flytrex for 1-mile drone deliveries in North Carolina

The future of last mile delivery includes drones

Extension of drone delivery taxis to takeoff with new FAA recommendations

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Artificial cell membrane channels composed of http://deliverjournal.com/artificial-cell-membrane-channels-composed-of/ Wed, 11 May 2022 02:00:28 +0000 http://deliverjournal.com/artificial-cell-membrane-channels-composed-of/

image: The graphic shows the bilayer structure of a living cell membrane, composed of phospholipids. A phospholipid consists of a hydrophilic or water loving head and a hydrophobic or water fearing tail. The hydrophobic tails are sandwiched between two layers of hydrophilic heads. In the center, a channel is represented, allowing the transport of biomolecules. The new study describes a process for creating artificial channels using DNA segments that insert into cell membranes and allow the reversible transit of various cargoes, including ions and proteins.
to see After

Credit: Biodesign Institute at ASU

Just as countries import a wide range of consumer goods across national borders, living cells are engaged in a vibrant import-export business. Their entry ports are sophisticated transport channels embedded in the protective membrane of a cell. The regulation of the types of goods that can cross the boundary zones formed by the two-layered membrane of the cell is essential for its proper functioning and survival.

In new research, Hao Yan, a professor at Arizona State University, along with ASU colleagues and international collaborators from University College London, describes the design and construction of artificial membrane channels, engineered at the using short stretches of DNA. DNA constructs behave like natural cellular channels or pores, providing selective transport of ions, proteins, and other cargoes, with enhanced functionality unavailable in their natural counterparts.

These innovative DNA nanochannels could one day be applied in a variety of scientific fields, ranging from biosensing and drug delivery applications to the creation of artificial cellular networks capable of capturing, concentrating, storing and autonomously delivering a microscopic cargo..

“Many biological pores and channels are closed by reversibility to allow ions or molecules to pass through,” says Yan. Here, we mimic these natural processes to design DNA nanopores that can be locked and opened in response to “key” or “lock” external molecules.

Professor Yan is the Milton D. Glick Professor Emeritus of Chemistry and Biochemistry at ASU and directs the Biodesign Center for Molecular Design and Biomimetics. He is also a professor in the School of Molecular Sciences at ASU.

The research results appear in the current issue of the journal Nature Communication.

All living cells are enveloped in a unique biological structure, the cell membrane. The scientific term for these membranes is phospholipid bilayer, which means that the membrane is formed from phosphate molecules attached to a fatty or lipid component to form an outer and inner membrane layer (see Figure 1).

These inner and outer membrane layers are much like the interior and exterior walls of a room. But unlike normal walls, the space between the inner and outer surfaces is fluid, resembling a sea. Additionally, cell membranes are said to be semi-permeable, allowing the designated entry or exit of cargo from the cell. Such transport typically occurs when transiting cargo binds to another molecule, changing the dynamics of the canal structure to allow entry into the cell, much like the opening of the Panama Canal.

Semi-permeable cell membranes are necessary to protect sensitive ingredients inside the cell from a harsh external environment, while allowing the transit of ions, nutrients, proteins, and other vital biomolecules.

Researchers including Yan have explored the possibility of synthetically creating selective membrane channels, using a technique known as DNA nanotechnology. The basic idea is simple. The double strands of DNA that form the genetic blueprint of all living organisms are held together by the base pairing of the molecule’s 4 nucleotides, labeled A, T, C, and G. A simple rule applies, namely that nucleotides A always pair with T and C with G. Thus, a segment of DNA ATTCTCG would form a complementary strand with CAAGAGC.

DNA base pairing allows for the synthetic construction of virtually unlimited network or 2- and 3-D nanostructures. Once a structure has been carefully designed, usually using a computer, the DNA segments can be mixed and will self-assemble in solution into the desired shape.

However, creating a semi-permeable channel using DNA nanotechnology has proven to be a daunting challenge. Conventional techniques have failed to replicate the structure and capabilities of natural membrane channels, and synthetic DNA nanopores typically only allow unidirectional transport of goods.

The new study describes an innovative method, allowing researchers to design and construct a synthetic membrane channel whose pore size allows for the transport of greater cargo than natural cellular channels. Unlike previous efforts to create DNA nanopores attached to membranes, the new technique builds the channel structure step by step, assembling the component DNA segments horizontally to the membrane, rather than vertically. The method allows the construction of nanopores with larger openings, allowing the transport of a greater range of biomolecules.

Additionally, the DNA design allows the channel to be selectively opened and closed by means of a hinged lid, fitted with a lock and key mechanism. The “keys” are made up of sequence-specific DNA strands that bind to the channel lid and trigger it to open or close.

In a series of experiments, the researchers demonstrate the ability of the DNA channel to successfully transport cargoes of varying sizes, ranging from tiny dye molecules to folded protein structures, some larger than the pore dimensions of natural membrane channels.

The researchers used atomic force microscopy and transmission electron microscopy to visualize the resulting structures, confirming that they met the original design specifications of the nanostructures.

Fluorescent dye molecules were used to verify that the DNA channels successfully pierced and inserted through the cell’s lipid bilayer, successfully providing selective entry of carrier molecules. The transport operation was completed within an hour of channel formation, a significant improvement over previous DNA nanopores, which typically require 5-8 hours for complete transit of the biomolecule.

DNA nanochannels can be used to capture and study proteins and look closely at their interactions with the biomolecules they bind to or study the rapid and complex folding and unfolding of proteins. These channels could also be used to exert precise control over biomolecules entering cells, providing a new window into targeted drug delivery. Many other possible applications will likely arise from the new ability to custom design artificial, self-assembled transport channels.


Warning: AAAS and EurekAlert! are not responsible for the accuracy of press releases posted on EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Decklar Resources Inc. begins shipping crude oil to http://deliverjournal.com/decklar-resources-inc-begins-shipping-crude-oil-to/ Mon, 09 May 2022 11:00:00 +0000 http://deliverjournal.com/decklar-resources-inc-begins-shipping-crude-oil-to/
  • Decklar and its joint venturer began loading crude oil into Oza oilfield trucks from storage tanks for delivery to Umugini Pipeline Infrastructure Limited (“UPIL”) crude handling facilities for onward transfer to the Shell Petroleum Development Company of Nigeria Limited (“SPDC” Joint Venture Forcados Oil Export Terminal via the Umugini Pipeline.
  • When the loading of crude oil from storage has reached 5,000 barrels, production from the Oza-1 well will start in order to allow truck shipments to UPIL to continue.

CALGARY, Alta., May 09, 2022 (GLOBE NEWSWIRE) — Decklar Resources Inc. (TSX-V: DKL) (OTCQX: DLKRF) (FSE: A1U1) (the “Company” or “Decklar”) is pleased to announce the start of the shipment of crude oil by trucks from the Oza oil field to the UPIL crude handling facilities for onward transfer to the SPDC Joint Venture Forcados oil export terminal through the Umugini pipeline.

Oza Field Oil Export Operations

Decklar and its joint venture partner Millenium Oil & Gas Company Limited (“Millenium”) began loading crude oil into trucks at the Oza oilfield from storage tanks for delivery to UPIL crude handling facilities for a later transfer to the SPDC Forcados Oil Terminal export joint venture via the Umugini pipeline.

Trucks are currently loaded from crude oil storage tanks at the Oza site which contain approximately 22,000 barrels of oil. When loading of crude oil from storage to trucks reaches approximately 5,000 barrels, production from the Oza-1 well in the storage reservoir will be restarted to allow for continued truck shipments to UPIL.

As previously announced, the 2022 development plans for the Oza field include:

  • the continuation of operations with local communities and contractors for the construction of the access road and associated infrastructure for a new oil well drilling platform;
  • drilling of the first new development well;
  • re-entry, re-completion and flow testing of the other two existing wells (Oza-2 and Oza-4), including connection to existing production facilities;
  • the installation of a central production facility and infrastructure connections for new wellsites to replace the current initial production facility; and
  • drilling additional development wells.

Development plans for the Oza field beyond 2022 also include up to five additional development wells.

Duncan Blount, CEO of Decklar Resources, said, “We are very pleased to announce the start of crude oil loading operations at the Oza field, which will soon lead to the company’s first delivery of oil to market. . This brings the company to the brink of the important milestone of starting full-time commercial production and transforming Decklar into a production and treasury company. We look forward to the start of new development drilling activities on the Oza field in the near future and the continued progress of development activities in the Company’s other fields. »

For more information:

Duncan T. Blount
Chairman and Chief Executive Officer Telephone: +1 305 890 6516
Email: dblount@decklarresources.com

David Halpin
Chief Financial Officer Phone: +1 403 816 3029
Email: david.halpin@decklarresources.com

Investor Relations: info@decklarresources.com

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Warning language

Certain statements made and information contained herein constitute “forward-looking information” (within the meaning of applicable Canadian securities laws), including, but not limited to, statements regarding: the restart of production at the Oza- 1 and the timing thereof, timing for the export or sale of stored barrels of oil, future commercial production from the Oza-1 well, the Company’s ability to finalize arrangements with local communities and contractors to begin construction of the access road and associated infrastructure for a new oil well drilling rig, drilling a new development well on the Oza field, the company’s plans for re-entry, re -completion and flow testing of the other two existing wells on the Oza field (Oza-2 and Oza-4), including linkages -in existing production facilities, Soc plans ity for the installation of a central production facility and infrastructure links for new well locations to replace the current initial production facility, potential for 5 new development wells in 2022 and development plans for 2022. All statements in this press release, other than statements of historical fact, are forward-looking statements. These statements and information (collectively, “forward-looking statements”) relate to future events or the Company’s future performance, prospects or business opportunities. There is no certainty that any definitive agreements relating to the Transaction will be entered into, or that any conditions precedent contained therein will be satisfied on terms satisfactory to the parties or at all.

All statements other than statements of historical fact may be forward-looking statements. Any statement that expresses or implies discussions regarding predictions, expectations, beliefs, plans, projections, goals, assumptions, or future events or performance (often, but not always, using words or phrases such that “seek”, “anticipate”, “plan”, “continue”, “estimate”, “expect”, “may”, “will”, “project”, “predict”, “potential”, “targeting “, “intend”, “could”, “could”, “should”, “believe” and similar expressions) are not statements of historical fact and may be “forward-looking statements”. Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause actual results or events to differ The Company believes that the expectations reflected in these forward-looking statements are reasonable, but no assurance can be given that such expectations will prove to be correct and such forward-looking statements should not be The Company does not place undue reliance on, and undertakes no obligation to, update such forward-looking statements, except as required by applicable law . These forward-looking statements involve risks and uncertainties related to, among other things, counterparty risk, changes in oil prices, results of exploration and development activities, competition in the oil and gas industry, uninsured risks, risks related to energy transition, regulatory changes, defaults in title, availability of materials and equipment, timeliness of government or other regulatory approvals, actual performance of facilities, availability financing on reasonable terms, availability of third-party service providers, equipment and processes relative to specifications and expectations, and unforeseen environmental impacts on operations. Actual results may differ materially from those expressed or implied by these forward-looking statements.

The Company does not guarantee that forward-looking statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements. The Company undertakes no obligation to revise or update these forward-looking statements after the date of this document or to revise them to reflect the occurrence of unforeseen future events, except as may be required under applicable laws. applicable securities.

]]> A retired Canadian Forces reservist delivers vital medical supplies to Ukrainian soldiers http://deliverjournal.com/a-retired-canadian-forces-reservist-delivers-vital-medical-supplies-to-ukrainian-soldiers/ Sat, 07 May 2022 08:00:00 +0000 http://deliverjournal.com/a-retired-canadian-forces-reservist-delivers-vital-medical-supplies-to-ukrainian-soldiers/

A Canadian veteran in kyiv teams up with a US tactical equipment supplier to deliver critical medical supplies to treat injured Ukrainian soldiers in the field.

Retired Canadian Armed Forces reservist Kevin Leach said he was tempted to join Ukraine’s fight against Russian forces as a foreign fighter. He said he changed his mind after his Ukrainian wife told him she would accompany him wherever he went.

Leach said that when he met American Nick Pappas – who was banned from taking up arms by his relative – they decided together to start a non-governmental organization (NGO) called Project Volya to help in another way.

“Seeing that we face an existential threat from Russia, I must contribute to victory,” Leach said from his apartment in Kyiv. “Anything else, I would be crushed. It would destroy my soul.”

With donations from several countries, including Canada, the two men ordered and shipped basic wartime supplies from the United States and Poland. Supplies include tourniquets, haemostatic gauze to dress wounds and chest seals to help injured people breathe.

“It’s about saving lives, keeping Ukraine in the fight,” said Leach, who from 2008 to 2018 served as an armored reconnaissance specialist sergeant.

“There are people who are injured but have their lives saved, are recovering and can return to combat or continue to contribute to the effort against Russia.”

WATCH / “Every day people get hurt”

“Every day there are injuries”

Kevin Leach of Project Volya says he wants to save the lives of Ukrainian fighters and Russian prisoners by donating medical supplies directly to Ukrainian soldiers. 0:28

The effort began when Pappas traveled to Lviv in western Ukraine during the first week of the Russian invasion. He loaded up duffel bags with $5,000 worth of medical supplies, thermal imaging telescopes and binoculars for the battlefield.

Pappas traveled to the Donbass region in southeastern Ukraine, donated his equipment to Ukrainian soldiers and showed them how to use it, Leach said.

Volya Project Purchasing Manager Nick Pappas (left) and manager Kevin Leach (right) in Warsaw, Poland. (Submitted)

“These guys were so excited for a stranger to come to their post and demonstrate through action that they cared,” Leach said.

Since then, Leach said, he and Pappas have set up a network of local drivers — including a Ukrainian army veteran — to ferry supplies across Poland’s border directly to fighters in eastern Israel. Ukraine. Small shipments are easier to deliver quickly to military units in need, he said.

“We can get things where they’re going without any red tape,” Leach said of their ties to the Ukrainian Armed Forces. “It never needs to go to a government warehouse.”

The project is just beginning. A shipment has arrived in the Donbass, a second is on its way from the United States and the NGO has collected enough money for another order from Poland.

Leach said it was all a big change for him. Since 2018, he has worked for the Canadian contingent of the Organization for Security and Cooperation in Europe (OSCE) monitoring team in Kyiv.

Prior to the Russian invasion, Kevin Leach worked with a Canadian mainland monitoring the conflict zone to record any ceasefire violations in the Donbass region. (Submitted)

Prior to Russia’s invasion in February, Leach’s job was to monitor the conflict zone in the Donetsk and Luhansk region for any ceasefire violations. In a room lined with television screens, Leach watched sophisticated cameras and thermal power supplies scanning the “line of contact” between government and non-government forces in the conflict zone.

Its role was to record explosions, heavy weapons in the front line or any other violation of the Minsk agreements.

“The idea was that it was going to avoid a war,” Leach said. “Unfortunately, it didn’t work out.”

In a separate effort, Canadian veteran and defense contractor Christopher Baxter said he is volunteering to help deliver medical supplies on a much larger scale.

Baxter runs the defense firm Caina-Longbranch; he said he had sent dozens of arms and ammunition shipments to US bases in Germany and Baghdad in previous conflicts. This time, he said, he’s handling logistics and working to arrange a cargo plane to collect more than $750,000 in medical supplies from the Care Convoy charity in Idaho.

The last shipment of tourniquets, haemostatic gauze and chest seals en route from Minnesota to Poland. (Submitted)

The charity said it received a large donation from a hospital which includes everything needed to set up and run a field hospital in Ukraine. The cargo is believed to include hospital beds, bandages, prostheses, surgical tools, crutches, medications and sutures, according to Care Convoy.

“The adventure is about getting a proper plane,” Baxter said.

After securing a private cargo plane through Ukrainian cargo carrier Antonov Airlines, Baxter said he was still trying to get the airport to waive landing fees and was asking for private donations to cover fuel and d other costs. He said he wanted the Canadian government to provide cargo space on C-17 military jets to transport private supplies to Ukraine.

WATCH / “We need to put people back together”

“We have to put people back together”

Ottawa defense contractor Christopher Baxter says weapons are not enough – Ukraine needs medical help in its fight against Russian forces. 0:15

“[Canadian] hospitals are upgrading and rotating inventory,” Baxter said. “Some of that is perfectly good. Yes [Ukrainians] can’t get donated items, they end up buying them on the black market, which could be inefficient, too expensive, or downright deadly.”

Baxter said the Canadian government may also set up Level 3 military hospitals in Ukraine’s neighboring countries – Poland, Slovakia and Romania – to help save potentially fatal people.

“We’ve gone from 2022 to 1945,” Baxter said. “We have a complete, outright war and a decimation of hospitals. Everything you can name is just wiped off the map. They literally need it all.”

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